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Concentration of non-myocyte proteins in arterial media of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

The most common inherited cause of vascular dementia and stroke, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), is caused by mutations in NOTCH3. Post-translationally altered NOTCH3 accumulates in the vascular media of CADASIL arteries in areas...

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Detalles Bibliográficos
Autores principales: Lee, Soo Jung, Kondepudi, Akhil, Young, Kelly Z., Zhang, Xiaojie, Cartee, Naw May Pearl, Chen, Jijun, Jang, Krystal Yujin, Xu, Gang, Borjigin, Jimo, Wang, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907840/
https://www.ncbi.nlm.nih.gov/pubmed/36753487
http://dx.doi.org/10.1371/journal.pone.0281094