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Understanding the self-assembly dynamics of A/T absent ‘four-way DNA junctions with sticky ends’ at altered physiological conditions through molecular dynamics simulations

Elucidation of structure and dynamics of alternative higher-order structures of DNA such as in branched form could be targeted for therapeutics designing. Herein, we are reporting the intrinsically dynamic and folds transitions of an unusual DNA junction with sequence d(CGGCGGCCGC)(4) which self-ass...

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Detalles Bibliográficos
Autores principales: Singh, Akanksha, Yadav, Ramesh Kumar, Shati, Ali, Kamboj, Nitin Kumar, Hasssan, Hesham, Bharadwaj, Shiv, Rana, Rashmi, Yadava, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907842/
https://www.ncbi.nlm.nih.gov/pubmed/36753480
http://dx.doi.org/10.1371/journal.pone.0278755