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Coordinated activity of a central pathway drives associative opioid analgesic tolerance

Opioid analgesic tolerance, a root cause of opioid overdose and misuse, can develop through an associative learning. Despite intensive research, the locus and central pathway subserving the associative opioid analgesic tolerance (AOAT) remains unclear. Using a combination of chemo/optogenetic manipu...

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Detalles Bibliográficos
Autores principales: Hou, Yiwen, Zou, Guichang, Wang, Xianglian, Guo, Hui, Ma, Xiao, Cheng, Xingyu, Xie, Zhiyong, Zuo, Xin, Xia, Jing, Mao, Huanhuan, Yuan, Man, Chen, Qi, Cao, Peng, Yang, Yupeng, Zhang, Li, Xiong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908028/
https://www.ncbi.nlm.nih.gov/pubmed/36753548
http://dx.doi.org/10.1126/sciadv.abo5627