Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis

BACKGROUND: Previous studies had limited power to assess the associations of circulating insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) with clinically relevant prostate cancer as a primary endpoint, and the association of genetically predicted IGF-I with aggressive prostate ca...

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Detalles Bibliográficos
Autores principales: Watts, Eleanor L, Perez-Cornago, Aurora, Fensom, Georgina K, Smith-Byrne, Karl, Noor, Urwah, Andrews, Colm D, Gunter, Marc J, Holmes, Michael V, Martin, Richard M, Tsilidis, Konstantinos K, Albanes, Demetrius, Barricarte, Aurelio, Bueno-de-Mesquita, H Bas, Cohn, Barbara A, Deschasaux-Tanguy, Melanie, Dimou, Niki L, Ferrucci, Luigi, Flicker, Leon, Freedman, Neal D, Giles, Graham G, Giovannucci, Edward L, Haiman, Christopher A, Hankey, Graham J, Holly, Jeffrey M P, Huang, Jiaqi, Huang, Wen-Yi, Hurwitz, Lauren M, Kaaks, Rudolf, Kubo, Tatsuhiko, Le Marchand, Loic, MacInnis, Robert J, Männistö, Satu, Metter, E Jeffrey, Mikami, Kazuya, Mucci, Lorelei A, Olsen, Anja W, Ozasa, Kotaro, Palli, Domenico, Penney, Kathryn L, Platz, Elizabeth A, Pollak, Michael N, Roobol, Monique J, Schaefer, Catherine A, Schenk, Jeannette M, Stattin, Pär, Tamakoshi, Akiko, Thysell, Elin, Tsai, Chiaojung Jillian, Touvier, Mathilde, Van Den Eeden, Stephen K, Weiderpass, Elisabete, Weinstein, Stephanie J, Wilkens, Lynne R, Yeap, Bu B, Allen, Naomi E, Key, Timothy J, Travis, Ruth C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908067/
https://www.ncbi.nlm.nih.gov/pubmed/35726641
http://dx.doi.org/10.1093/ije/dyac124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908067/
https://www.ncbi.nlm.nih.gov/pubmed/35726641
http://dx.doi.org/10.1093/ije/dyac124

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