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Can we predict T cell specificity with digital biology and machine learning?

Recent advances in machine learning and experimental biology have offered breakthrough solutions to problems such as protein structure prediction that were long thought to be intractable. However, despite the pivotal role of the T cell receptor (TCR) in orchestrating cellular immunity in health and...

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Detalles Bibliográficos
Autores principales: Hudson, Dan, Fernandes, Ricardo A., Basham, Mark, Ogg, Graham, Koohy, Hashem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908307/
https://www.ncbi.nlm.nih.gov/pubmed/36755161
http://dx.doi.org/10.1038/s41577-023-00835-3