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HIV silencing and cell survival signatures in infected T cell reservoirs

Rare CD4 T cells that contain HIV under antiretroviral therapy represent an important barrier to HIV cure(1–3), but the infeasibility of isolating and characterizing these cells in their natural state has led to uncertainty about whether they possess distinctive attributes that HIV cure-directed the...

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Detalles Bibliográficos
Autores principales: Clark, Iain C., Mudvari, Prakriti, Thaploo, Shravan, Smith, Samuel, Abu-Laban, Mohammad, Hamouda, Mehdi, Theberge, Marc, Shah, Sakshi, Ko, Sung Hee, Pérez, Liliana, Bunis, Daniel G., Lee, James S., Kilam, Divya, Zakaria, Saami, Choi, Sally, Darko, Samuel, Henry, Amy R., Wheeler, Michael A., Hoh, Rebecca, Butrus, Salwan, Deeks, Steven G., Quintana, Francisco J., Douek, Daniel C., Abate, Adam R., Boritz, Eli A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908556/
https://www.ncbi.nlm.nih.gov/pubmed/36599978
http://dx.doi.org/10.1038/s41586-022-05556-6