IgD shapes the pre-immune naïve B cell compartment in humans

B cell maturation and immunoglobulin (Ig) repertoire selection are governed by expression of a functional B cell receptor (BCR). Naïve B cells co-express their BCR as IgM and IgD isotype. However, the role of the additionally expressed IgD on naïve B cells is not known. Here we assessed the impact o...

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Detalles Bibliográficos
Autores principales: Dirks, Johannes, Andres, Oliver, Paul, Luisa, Manukjan, Georgi, Schulze, Harald, Morbach, Henner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908586/
https://www.ncbi.nlm.nih.gov/pubmed/36776874
http://dx.doi.org/10.3389/fimmu.2023.1096019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908586/
https://www.ncbi.nlm.nih.gov/pubmed/36776874
http://dx.doi.org/10.3389/fimmu.2023.1096019

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