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IgD shapes the pre-immune naïve B cell compartment in humans
B cell maturation and immunoglobulin (Ig) repertoire selection are governed by expression of a functional B cell receptor (BCR). Naïve B cells co-express their BCR as IgM and IgD isotype. However, the role of the additionally expressed IgD on naïve B cells is not known. Here we assessed the impact o...
Autores principales: | Dirks, Johannes, Andres, Oliver, Paul, Luisa, Manukjan, Georgi, Schulze, Harald, Morbach, Henner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908586/ https://www.ncbi.nlm.nih.gov/pubmed/36776874 http://dx.doi.org/10.3389/fimmu.2023.1096019 |
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