Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and K(Ca)3.1 ion channels, but involves phosphoinositide 3-kinase

The microenvironment of proliferative and aggressive tumours, such as the brain tumour glioblastoma multiforme (GBM), is often acidic, hypoxic, and nutrient deficient. Acid-sensing ion channels (ASICs) are proton-sensitive Na(+) channels that have been proposed to play a role in pH sensing and in mo...

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Detalles Bibliográficos
Autores principales: Cortés Franco, Klaus-Daniel, Brakmann, Ilka C., Feoktistova, Maria, Panayotova-Dimitrova, Diana, Gründer, Stefan, Tian, Yuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Signaling and Cell Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908655/
https://www.ncbi.nlm.nih.gov/pubmed/36522586
http://dx.doi.org/10.1007/s00424-022-02781-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908655/
https://www.ncbi.nlm.nih.gov/pubmed/36522586
http://dx.doi.org/10.1007/s00424-022-02781-w

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