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Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy

The renal renin-angiotensin system (RAS) is involved in the development of chronic kidney disease. Here, we investigated whether mice with reduced renal angiotensin I-converting enzyme (ACE(−/−)) are protected against aristolochic acid nephropathy (AAN). To further elucidate potential molecular mech...

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Detalles Bibliográficos
Autores principales: Juretzko, Annett, Steinbach, Antje, Witte, Jeannine, Hannemann, Anke, Miehe, Bärbel, Siegerist, Florian, Wolke, Carmen, Stracke, Sylvia, Rettig, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908662/
https://www.ncbi.nlm.nih.gov/pubmed/36520238
http://dx.doi.org/10.1007/s00424-022-02779-4