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Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy
The renal renin-angiotensin system (RAS) is involved in the development of chronic kidney disease. Here, we investigated whether mice with reduced renal angiotensin I-converting enzyme (ACE(−/−)) are protected against aristolochic acid nephropathy (AAN). To further elucidate potential molecular mech...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908662/ https://www.ncbi.nlm.nih.gov/pubmed/36520238 http://dx.doi.org/10.1007/s00424-022-02779-4 |