Hepatoprotective effect of nicorandil against acetaminophen-induced oxidative stress and hepatotoxicity in mice via modulating NO synthesis

Acetaminophen (APAP) overdose can produce hepatotoxicity and consequently liver damage. This study investigated the hepatoprotective impacts of nicorandil on hepatic damage induced by APAP. Nicorandil was administered orally (100 mg/kg) for seven days before APAP challenge (500 mg/kg, ip). Pretreatm...

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Detalles Bibliográficos
Autores principales: El-Kashef, Dalia H., Sharawy, Maha H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908717/
https://www.ncbi.nlm.nih.gov/pubmed/36149558
http://dx.doi.org/10.1007/s11356-022-23139-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908717/
https://www.ncbi.nlm.nih.gov/pubmed/36149558
http://dx.doi.org/10.1007/s11356-022-23139-w

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