Influence of Side Chain Conformation on the Activity of Glycosidase Inhibitors

Substrate side chain conformation impacts reactivity during glycosylation and glycoside hydrolysis and is restricted by many glycosidases and glycosyltransferases during catalysis. We show that the side chains of gluco and manno iminosugars can be restricted to predominant conformations by strategic...

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Detalles Bibliográficos
Autores principales: Tseng, Po‐Sen, Ande, Chennaiah, Moremen, Kelley W., Crich, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908843/
https://www.ncbi.nlm.nih.gov/pubmed/36573850
http://dx.doi.org/10.1002/anie.202217809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908843/
https://www.ncbi.nlm.nih.gov/pubmed/36573850
http://dx.doi.org/10.1002/anie.202217809

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