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Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT

A proper understanding of disease etiology will require longitudinal systems-scale reconstruction of the multitiered architecture of eukaryotic signaling. Here we combine state-of-the-art data acquisition platforms and bioinformatics tools to devise PAMAF, a workflow that simultaneously examines twe...

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Detalles Bibliográficos
Autores principales: Paul, Indranil, Bolzan, Dante, Youssef, Ahmed, Gagnon, Keith A., Hook, Heather, Karemore, Gopal, Oliphant, Michael U. J., Lin, Weiwei, Liu, Qian, Phanse, Sadhna, White, Carl, Padhorny, Dzmitry, Kotelnikov, Sergei, Chen, Christopher S., Hu, Pingzhao, Denis, Gerald V., Kozakov, Dima, Raught, Brian, Siggers, Trevor, Wuchty, Stefan, Muthuswamy, Senthil K., Emili, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908882/
https://www.ncbi.nlm.nih.gov/pubmed/36755019
http://dx.doi.org/10.1038/s41467-023-36122-x