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Gasdermin D inhibition ameliorates neutrophil mediated brain damage in acute ischemic stroke
Acute ischemic stroke (AIS) induces high level of neutrophils, which correlates inversely with patient survival. Pyroptosis induced by gasdermin D (GSDMD) has been shown to have an important role in the pathophysiology of several inflammatory disorders. The role of GSDMD in the high level of neutrop...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908898/ https://www.ncbi.nlm.nih.gov/pubmed/36755018 http://dx.doi.org/10.1038/s41420-023-01349-6 |