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Gasdermin D inhibition ameliorates neutrophil mediated brain damage in acute ischemic stroke

Acute ischemic stroke (AIS) induces high level of neutrophils, which correlates inversely with patient survival. Pyroptosis induced by gasdermin D (GSDMD) has been shown to have an important role in the pathophysiology of several inflammatory disorders. The role of GSDMD in the high level of neutrop...

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Detalles Bibliográficos
Autores principales:	Hu, Ruiyao, Liang, Jing, Ding, Lan, Zhang, Wan, Wang, Yuying, Zhang, Yige, Zhang, Ding, Pei, Lulu, Liu, Xinjing, Xia, Zongping, Xu, Yuming, Song, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908898/ https://www.ncbi.nlm.nih.gov/pubmed/36755018 http://dx.doi.org/10.1038/s41420-023-01349-6

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