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TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity

The cortical actin cytoskeleton plays a critical role in maintaining intestinal epithelial integrity, and the loss of this architecture leads to chronic inflammation, as seen in inflammatory bowel disease (IBD). However, the exact mechanisms underlying aberrant actin remodeling in pathological state...

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Detalles Bibliográficos
Autores principales: Kang, Sujin, Kim, Jaekyung, Park, Areum, Koh, Minsoo, Shin, Wonji, Park, Gayoung, Lee, Taeyun A., Kim, Hyung Jin, Han, Heonjong, Kim, Yongbo, Choi, Myung Kyung, Park, Jae Hyung, Lee, Eunhye, Cho, Hyun-Soo, Park, Hyun Woo, Cheon, Jae Hee, Lee, Sungwook, Park, Boyoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908899/
https://www.ncbi.nlm.nih.gov/pubmed/36755029
http://dx.doi.org/10.1038/s41467-023-36424-0