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TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity
The cortical actin cytoskeleton plays a critical role in maintaining intestinal epithelial integrity, and the loss of this architecture leads to chronic inflammation, as seen in inflammatory bowel disease (IBD). However, the exact mechanisms underlying aberrant actin remodeling in pathological state...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908899/ https://www.ncbi.nlm.nih.gov/pubmed/36755029 http://dx.doi.org/10.1038/s41467-023-36424-0 |