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Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies

Impairments in protein folding in the endoplasmic reticulum (ER) lead to a condition called ER stress, which can trigger apoptosis via the mitochondrial or the death receptor (extrinsic) pathway. There is controversy concerning involvement of the death receptor (DR)4 and DR5-Caspase-8 –Bid pathway i...

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Detalles Bibliográficos
Autores principales: Favaro, Francesca, Both, Demi, Derks, Ingrid A. M., Spaargaren, Marcel, Muñoz-Pinedo, Cristina, Eldering, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908905/
https://www.ncbi.nlm.nih.gov/pubmed/36755015
http://dx.doi.org/10.1038/s41389-023-00450-w