A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis

Although elevated levels of anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA), the in vivo functions of these antibodies remain unclear. Here, we have expressed monoclonal ACPAs derived from patients with RA, and analyzed their functions in mice, as well as th...

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Detalles Bibliográficos
Autores principales: He, Yibo, Ge, Changrong, Moreno-Giró, Àlex, Xu, Bingze, Beusch, Christian M., Sandor, Katalin, Su, Jie, Cheng, Lei, Lönnblom, Erik, Lundqvist, Christina, Slot, Linda M., Tong, Dongmei, Urbonaviciute, Vilma, Liang, Bibo, Li, Taotao, Lahore, Gonzalo Fernandez, Aoun, Mike, Malmström, Vivianne, Rispens, Theo, Ernfors, Patrik, Svensson, Camilla I., Scherer, Hans Ulrich, Toes, René E. M., Gjertsson, Inger, Ekwall, Olov, Zubarev, Roman A., Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908943/
https://www.ncbi.nlm.nih.gov/pubmed/36754962
http://dx.doi.org/10.1038/s41467-023-36257-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908943/
https://www.ncbi.nlm.nih.gov/pubmed/36754962
http://dx.doi.org/10.1038/s41467-023-36257-x

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