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A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis
Although elevated levels of anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA), the in vivo functions of these antibodies remain unclear. Here, we have expressed monoclonal ACPAs derived from patients with RA, and analyzed their functions in mice, as well as th...
Autores principales: | He, Yibo, Ge, Changrong, Moreno-Giró, Àlex, Xu, Bingze, Beusch, Christian M., Sandor, Katalin, Su, Jie, Cheng, Lei, Lönnblom, Erik, Lundqvist, Christina, Slot, Linda M., Tong, Dongmei, Urbonaviciute, Vilma, Liang, Bibo, Li, Taotao, Lahore, Gonzalo Fernandez, Aoun, Mike, Malmström, Vivianne, Rispens, Theo, Ernfors, Patrik, Svensson, Camilla I., Scherer, Hans Ulrich, Toes, René E. M., Gjertsson, Inger, Ekwall, Olov, Zubarev, Roman A., Holmdahl, Rikard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908943/ https://www.ncbi.nlm.nih.gov/pubmed/36754962 http://dx.doi.org/10.1038/s41467-023-36257-x |
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