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AlphaFold2 reveals commonalities and novelties in protein structure space for 21 model organisms

Deep-learning (DL) methods like DeepMind’s AlphaFold2 (AF2) have led to substantial improvements in protein structure prediction. We analyse confident AF2 models from 21 model organisms using a new classification protocol (CATH-Assign) which exploits novel DL methods for structural comparison and cl...

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Detalles Bibliográficos
Autores principales: Bordin, Nicola, Sillitoe, Ian, Nallapareddy, Vamsi, Rauer, Clemens, Lam, Su Datt, Waman, Vaishali P., Sen, Neeladri, Heinzinger, Michael, Littmann, Maria, Kim, Stephanie, Velankar, Sameer, Steinegger, Martin, Rost, Burkhard, Orengo, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908985/
https://www.ncbi.nlm.nih.gov/pubmed/36755055
http://dx.doi.org/10.1038/s42003-023-04488-9