Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis

Labetalol is used for the therapy of hypertension in preeclampsia. Preeclampsia is characterized by high soluble endoglin (sEng) concentration in plasma and coincides with intrahepatic cholestasis during pregnancy (ICP), which threatens the fetus with the toxicity of cumulating bile acids (BA). Ther...

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Detalles Bibliográficos
Autores principales: Cristina Igreja Sá, Ivone, Tripska, Katarina, Alaei Faradonbeh, Fatemeh, Hroch, Milos, Lastuvkova, Hana, Schreiberova, Jolana, Kacerovsky, Marian, Pericacho, Miguel, Nachtigal, Petr, Micuda, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909014/
https://www.ncbi.nlm.nih.gov/pubmed/36778021
http://dx.doi.org/10.3389/fphar.2023.1116422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909014/
https://www.ncbi.nlm.nih.gov/pubmed/36778021
http://dx.doi.org/10.3389/fphar.2023.1116422

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