Mettl3 deficiency leads to the upregulation of Cav1.2 and increases arrhythmia susceptibility in mice: Mettl3 regulates L-type Ca currents of cardiomyocytes

Methyltransferase-like 3 (Mettl3) is a component of methyltransferase complex that mediates m (6)A modification of RNAs, and participates in multiple biological processes. However, the role of Mettl3 in cardiac electrophysiology remains unknown. This study aims to explore the ventricular arrhythmia...

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Detalles Bibliográficos
Autores principales: Shi, Ling, Jin, Xuexin, Li, Zheng, Gong, Rui, Guo, Yang, Ma, Jiudong, Zhang, Yang, Cai, Benzhi, Yang, Baofeng, Gong, Dongmei, Pan, Zhenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909299/
https://www.ncbi.nlm.nih.gov/pubmed/35130614
http://dx.doi.org/10.3724/abbs.2021025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909299/
https://www.ncbi.nlm.nih.gov/pubmed/35130614
http://dx.doi.org/10.3724/abbs.2021025

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