Mettl3 deficiency leads to the upregulation of Cav1.2 and increases arrhythmia susceptibility in mice: Mettl3 regulates L-type Ca currents of cardiomyocytes

Methyltransferase-like 3 (Mettl3) is a component of methyltransferase complex that mediates m (6)A modification of RNAs, and participates in multiple biological processes. However, the role of Mettl3 in cardiac electrophysiology remains unknown. This study aims to explore the ventricular arrhythmia...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Ling, Jin, Xuexin, Li, Zheng, Gong, Rui, Guo, Yang, Ma, Jiudong, Zhang, Yang, Cai, Benzhi, Yang, Baofeng, Gong, Dongmei, Pan, Zhenwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909299/
https://www.ncbi.nlm.nih.gov/pubmed/35130614
http://dx.doi.org/10.3724/abbs.2021025

Ejemplares similares

Ejemplares similares