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Overexpression CPT1A reduces lipid accumulation via PPARα/CD36 axis to suppress the cell proliferation in ccRCC: CPT1A inhibits ccRCC cell proliferation via PPARα/CD36 axis

Clear cell renal carcinoma (ccRCC) is histologically defined by its cytoplasmic lipid deposits. Lipid metabolism disorder largely increases the risk of ccRCC. In this study, we aimed to investigate the biological functions and molecular mechanisms of carnitine palmitoyl transferase 1A (CPT1A) in ccR...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Zhao, Hongbo, Ren, Zhongkun, Yi, Xiaojia, Zhang, Qiao, Yang, Zhe, Kuang, Yingmin, Zhu, Yuechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909300/
https://www.ncbi.nlm.nih.gov/pubmed/35130611
http://dx.doi.org/10.3724/abbs.2021023