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SY-707, an ALK/FAK/IGF1R inhibitor, suppresses growth and metastasis of breast cancer cells: SY-707 is an ALK/FAK/IGF1R inhibitor

Focal adhesion kinase (FAK), a multi-functional cytoplasmic tyrosine kinase, plays a critical role in cancer migration, proliferation and metastasis via regulating multiple signaling pathways. SY-707 is an anaplastic lymphoma kinase (ALK)/FAK/type 1 insulin-like growth factor receptor (IGF1R) multi-...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Sun, Yinghui, Liu, Shuang, Niu, Jing, Liu, Xijie, Chu, Qiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909315/
https://www.ncbi.nlm.nih.gov/pubmed/35538024
http://dx.doi.org/10.3724/abbs.2022008