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Parameterization of a single H-bond in Orange Carotenoid Protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems

Introduction: Dissecting the intricate networks of covalent and non-covalent interactions that stabilize complex protein structures is notoriously difficult and requires subtle atomic-level exchanges to precisely affect local chemical functionality. The function of the Orange Carotenoid Protein (OCP...

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Detalles Bibliográficos
Autores principales: Moldenhauer, Marcus, Tseng, Hsueh-Wei, Kraskov, Anastasia, Tavraz, Neslihan N., Yaroshevich, Igor A., Hildebrandt, Peter, Sluchanko, Nikolai N., Hochberg, Georg A., Essen, Lars-Oliver, Budisa, Nediljko, Korf, Lukas, Maksimov, Eugene G., Friedrich, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909426/
https://www.ncbi.nlm.nih.gov/pubmed/36776742
http://dx.doi.org/10.3389/fmolb.2023.1072606