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Parameterization of a single H-bond in Orange Carotenoid Protein by atomic mutation reveals principles of evolutionary design of complex chemical photosystems
Introduction: Dissecting the intricate networks of covalent and non-covalent interactions that stabilize complex protein structures is notoriously difficult and requires subtle atomic-level exchanges to precisely affect local chemical functionality. The function of the Orange Carotenoid Protein (OCP...
Autores principales: | Moldenhauer, Marcus, Tseng, Hsueh-Wei, Kraskov, Anastasia, Tavraz, Neslihan N., Yaroshevich, Igor A., Hildebrandt, Peter, Sluchanko, Nikolai N., Hochberg, Georg A., Essen, Lars-Oliver, Budisa, Nediljko, Korf, Lukas, Maksimov, Eugene G., Friedrich, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909426/ https://www.ncbi.nlm.nih.gov/pubmed/36776742 http://dx.doi.org/10.3389/fmolb.2023.1072606 |
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