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The human MRS2 magnesium-binding domain is a regulatory feedback switch for channel activity

Mitochondrial RNA splicing 2 (MRS2) forms a magnesium (Mg(2+)) entry protein channel in mitochondria. Whereas MRS2 contains two transmembrane domains constituting a pore on the inner mitochondrial membrane, most of the protein resides within the matrix. Yet, the precise structural and functional rol...

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Detalles Bibliográficos
Autores principales: Uthayabalan, Sukanthathulse, Vishnu, Neelanjan, Madesh, Muniswamy, Stathopulos, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909464/
https://www.ncbi.nlm.nih.gov/pubmed/36754568
http://dx.doi.org/10.26508/lsa.202201742