Cargando…
The human MRS2 magnesium-binding domain is a regulatory feedback switch for channel activity
Mitochondrial RNA splicing 2 (MRS2) forms a magnesium (Mg(2+)) entry protein channel in mitochondria. Whereas MRS2 contains two transmembrane domains constituting a pore on the inner mitochondrial membrane, most of the protein resides within the matrix. Yet, the precise structural and functional rol...
Autores principales: | Uthayabalan, Sukanthathulse, Vishnu, Neelanjan, Madesh, Muniswamy, Stathopulos, Peter B |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909464/ https://www.ncbi.nlm.nih.gov/pubmed/36754568 http://dx.doi.org/10.26508/lsa.202201742 |
Ejemplares similares
-
Limiting Mrs2-dependent mitochondrial Mg(2+) uptake induces metabolic programming in prolonged dietary stress
por: Madaris, Travis R., et al.
Publicado: (2023) -
Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms
por: Lai, Louis Tung Faat, et al.
Publicado: (2023) -
Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms
por: Lai, Louis Tung Faat, et al.
Publicado: (2023) -
VDAC-dependent permeabilization of the outer mitochondrial membrane by superoxide induces rapid and massive cytochrome c release
por: Madesh, Muniswamy, et al.
Publicado: (2001) -
Resolving macrophage polarization through distinct Ca(2+) entry channel that maintains intracellular signaling and mitochondrial bioenergetics
por: Nascimento Da Conceicao, Viviane, et al.
Publicado: (2021)