Cargando…

Application of ddPCR in detection of the status and abundance of EGFR T790M mutation in the plasma samples of non-small cell lung cancer patients

BACKGROUND/OBJECTIVE: The third-generation epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitor (TKIs), such as osimertinib, designed for targeting the acquired drug-resistant mutation of EGFR T790M, was approved as the first-line therapy for advanced EGFR-mutated non-small cell lung c...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hui, Hu, Yi, Wang, Yan, Song, Xia, Hu, Ying, Ma, Li, Yang, Xinjie, Li, Kun, Qin, Na, Wang, Jinghui, Lv, Jialin, Li, Xi, Zhang, Xinyong, Zhang, Quan, Wu, Yuhua, Yao, Guangyin, Zhang, Shucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909534/
https://www.ncbi.nlm.nih.gov/pubmed/36776375
http://dx.doi.org/10.3389/fonc.2022.942123