Addressing blood-brain-tumor-barrier heterogeneity in pediatric brain tumors with innovative preclinical models

Brain tumors represent the leading cause of disease-related mortality and morbidity in children, with effective treatments urgently required. One factor limiting the effectiveness of systemic therapy is the blood-brain-barrier (BBB), which limits the brain penetration of many anticancer drugs. BBB i...

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Detalles Bibliográficos
Autores principales: Morris, Elysse K., Daignault-Mill, Sheena, Stehbens, Samantha J., Genovesi, Laura A., Lagendijk, Anne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909546/
https://www.ncbi.nlm.nih.gov/pubmed/36776301
http://dx.doi.org/10.3389/fonc.2023.1101522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909546/
https://www.ncbi.nlm.nih.gov/pubmed/36776301
http://dx.doi.org/10.3389/fonc.2023.1101522

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