SLC-0111, an inhibitor of carbonic anhydrase IX, attenuates hepatoblastoma cell viability and migration

BACKGROUND: In response to hypoxia, tumor cells undergo transcriptional reprogramming including upregulation of carbonic anhydrase (CA) IX, a metalloenzyme that maintains acid-base balance. CAIX overexpression has been shown to correlate with poor prognosis in various cancers, but the role of this C...

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Detalles Bibliográficos
Autores principales: Eloranta, Katja, Pihlajoki, Marjut, Liljeström, Emmi, Nousiainen, Ruth, Soini, Tea, Lohi, Jouko, Cairo, Stefano, Wilson, David B., Parkkila, Seppo, Heikinheimo, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909558/
https://www.ncbi.nlm.nih.gov/pubmed/36776327
http://dx.doi.org/10.3389/fonc.2023.1118268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909558/
https://www.ncbi.nlm.nih.gov/pubmed/36776327
http://dx.doi.org/10.3389/fonc.2023.1118268

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