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Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis

IMPORTANCE: Comorbidities and genetic correlations between gastrointestinal tract diseases and psychiatric disorders have been widely reported, with the gut-brain axis (GBA) hypothesized as a potential biological basis. However, the degree to which the shared genetic determinants are involved in the...

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Detalles Bibliográficos
Autores principales: Gong, Weiming, Guo, Ping, Li, Yuanming, Liu, Lu, Yan, Ran, Liu, Shuai, Wang, Shukang, Xue, Fuzhong, Zhou, Xiang, Yuan, Zhongshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909581/
https://www.ncbi.nlm.nih.gov/pubmed/36753304
http://dx.doi.org/10.1001/jamapsychiatry.2022.4974