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Aberrant association of chromatin with nuclear periphery induced by Rif1 leads to mitotic defect
The architecture and nuclear location of chromosomes affect chromatin events. Rif1, a crucial regulator of replication timing, recognizes G-quadruplex and inhibits origin firing over the 50–100-kb segment in fission yeast, Schizosaccharomyces pombe, leading us to postulate that Rif1 may generate chr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909590/ https://www.ncbi.nlm.nih.gov/pubmed/36750367 http://dx.doi.org/10.26508/lsa.202201603 |