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Aberrant association of chromatin with nuclear periphery induced by Rif1 leads to mitotic defect

The architecture and nuclear location of chromosomes affect chromatin events. Rif1, a crucial regulator of replication timing, recognizes G-quadruplex and inhibits origin firing over the 50–100-kb segment in fission yeast, Schizosaccharomyces pombe, leading us to postulate that Rif1 may generate chr...

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Detalles Bibliográficos
Autores principales: Kanoh, Yutaka, Ueno, Masaru, Hayano, Motoshi, Kudo, Satomi, Masai, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909590/
https://www.ncbi.nlm.nih.gov/pubmed/36750367
http://dx.doi.org/10.26508/lsa.202201603