Novel and efficient method for the reconstruction of adenoviruses through isothermal assembly and its potential applications

Adenovirus based vectors are useful tools for vaccine development, gene therapy, and oncolytic virotherapy. Here we describe a novel approach for the genetic engineering of any portion of the adenovirus genome and the reconstruction of either fully replication competent or defective virions. This in...

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Detalles Bibliográficos
Autores principales: Wen, Ke, Resch, Matthew D., Mazboudi, Ryan, Mulhall Maasz, Hannah, Galarza, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medical Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909595/
https://www.ncbi.nlm.nih.gov/pubmed/36776626
http://dx.doi.org/10.3389/fmedt.2023.1095198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909595/
https://www.ncbi.nlm.nih.gov/pubmed/36776626
http://dx.doi.org/10.3389/fmedt.2023.1095198

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