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Novel and efficient method for the reconstruction of adenoviruses through isothermal assembly and its potential applications
Adenovirus based vectors are useful tools for vaccine development, gene therapy, and oncolytic virotherapy. Here we describe a novel approach for the genetic engineering of any portion of the adenovirus genome and the reconstruction of either fully replication competent or defective virions. This in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909595/ https://www.ncbi.nlm.nih.gov/pubmed/36776626 http://dx.doi.org/10.3389/fmedt.2023.1095198 |