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Chromatographic Phospholipid Trapping for Automated H/D Exchange Mass Spectrometry of Membrane Protein–Lipid Assemblies

[Image: see text] Lipid interactions modulate the function, folding, structure, and organization of membrane proteins. Hydrogen/deuterium exchange mass spectrometry (HDX-MS) has emerged as a useful tool to understand the structural dynamics of these proteins within lipid environments. Lipids, howeve...

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Detalles Bibliográficos
Autores principales: Hammerschmid, Dietmar, Calvaresi, Valeria, Bailey, Chloe, Russell Lewis, Benjamin, Politis, Argyris, Morris, Michael, Denbigh, Laetitia, Anderson, Malcolm, Reading, Eamonn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909672/
https://www.ncbi.nlm.nih.gov/pubmed/36706021
http://dx.doi.org/10.1021/acs.analchem.2c04876