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Methods for the isolation and analysis of Aβ from postmortem brain

Amyloid β-protein (Aβ) plays an initiating role in Alzheimer’s disease (AD), but only a small number of groups have studied Aβ extracted from human brain. Most prior studies have utilized synthetic Aβ peptides, but the relevance of these test tube experiments to the conditions that prevail in AD is...

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Detalles Bibliográficos
Autores principales: Hong, Wei, Liu, Wen, Desousa, Alexandra O., Young-Pearse, Tracy, Walsh, Dominic M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909698/
https://www.ncbi.nlm.nih.gov/pubmed/36777642
http://dx.doi.org/10.3389/fnins.2023.1108715