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Construction of Genetically Encoded Biosensors to Monitor Subcellular Compartment-Specific Glutathione Response to Chemotherapeutic Drugs in Acute Myeloid Leukemia Cells

[Image: see text] Glutathione (GSH), the constituent of the redox buffer system, is a scavenger of reactive oxygen species (ROS), and its ratio to oxidized glutathione (GSSG) is a key indicator of oxidative stress in the cell. Acute myeloid leukemia (AML) is a highly aggressive hematopoietic maligna...

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Detalles Bibliográficos
Autores principales:	Abbas, Ghulam, Cui, Mengmeng, Wang, Dianbing, Li, Min, Zhang, Xian-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909732/ https://www.ncbi.nlm.nih.gov/pubmed/36701391 http://dx.doi.org/10.1021/acs.analchem.2c04255

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