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Extensive blood transcriptome analysis reveals cellular signaling networks activated by circulating glycocalyx components reflecting vascular injury in COVID-19

BACKGROUND: Degradation of the endothelial protective glycocalyx layer during COVID-19 infection leads to shedding of major glycocalyx components. These circulating proteins and their degradation products may feedback on immune and endothelial cells and activate molecular signaling cascades in COVID...

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Detalles Bibliográficos
Autores principales: Borrmann, Melanie, Brandes, Florian, Kirchner, Benedikt, Klein, Matthias, Billaud, Jean-Noël, Reithmair, Marlene, Rehm, Markus, Schelling, Gustav, Pfaffl, Michael W., Meidert, Agnes S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909741/
https://www.ncbi.nlm.nih.gov/pubmed/36776845
http://dx.doi.org/10.3389/fimmu.2023.1129766