Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4

INTRODUCTION: HIV-1 persists in resting CD4(+) T-cells despite antiretroviral therapy (ART). Determining the cell surface markers that enrich for genetically-intact HIV-1 genomes is vital in developing targeted curative strategies. Previous studies have found that HIV-1 proviral DNA is enriched in C...

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Detalles Bibliográficos
Autores principales: Fisher, Katie, Schlub, Timothy E., Boyer, Zoe, Rasmussen, Thomas A., Rhodes, Ajantha, Hoh, Rebecca, Hecht, Frederick M., Deeks, Steven G., Lewin, Sharon R., Palmer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909745/
https://www.ncbi.nlm.nih.gov/pubmed/36776833
http://dx.doi.org/10.3389/fimmu.2023.1064346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909745/
https://www.ncbi.nlm.nih.gov/pubmed/36776833
http://dx.doi.org/10.3389/fimmu.2023.1064346

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