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Exploring SPK98 for the Selective Sensitization of ATM- or P53-Deficient Cancer Cells
[Image: see text] Frequent mutation in the ATM/P53 signaling pathway has been documented in many human cancers. Reportedly, cancer cells with deficient P53/ATM pathways depend on functional Ataxia-telangiectasia and Rad3-related (ATR) protein for survival. This has prompted research in developing AT...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909806/ https://www.ncbi.nlm.nih.gov/pubmed/36777575 http://dx.doi.org/10.1021/acsomega.2c07356 |