Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis

BACKGROUND: Toxicity assessment for regulatory purposes is starting to move away from traditional in vivo methods and towards new approach methodologies (NAM) such as high-throughput in vitro models and computational tools. For materials with limited hazard information, utilising quantitative Advers...

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Detalles Bibliográficos
Autores principales: McLean, Polly, Mueller, William, Gosens, Ilse, Cassee, Flemming R., Rothen-Rutishauser, Barbara, Boyles, Matthew, Tran, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909881/
https://www.ncbi.nlm.nih.gov/pubmed/36759844
http://dx.doi.org/10.1186/s12989-023-00516-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909881/
https://www.ncbi.nlm.nih.gov/pubmed/36759844
http://dx.doi.org/10.1186/s12989-023-00516-y

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