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Tamoxifen induces radioresistance through NRF2-mediated metabolic reprogramming in breast cancer

BACKGROUND: Recently, we reported that tamoxifen-resistant (TAM-R) breast cancer cells are cross-resistant to irradiation. Here, we investigated the mechanisms associated with tamoxifen-induced radioresistance, aiming to prevent or reverse resistance and improve breast cancer treatment. METHODS: Wil...

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Detalles Bibliográficos
Autores principales: Naumann, F. V., Sweep, F. C. G. J., Adema, G. J., Peeters, W. J. M., Martens, J. W. M., Bussink, J., Span, P. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909892/
https://www.ncbi.nlm.nih.gov/pubmed/36755288
http://dx.doi.org/10.1186/s40170-023-00304-4