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ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway

The mechanisms of self-renewal and pluripotency maintenance of human pluripotent stem cells (hPSCs) have not been fully elucidated, especially for the role of those poorly characterized long noncoding RNAs (lncRNAs). ESRG is a lncRNA highly expressed in hPSCs, and its functional roles are being exte...

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Detalles Bibliográficos
Autores principales: Li, Shasha, Liu, Hui, Liu, Weidong, Shi, Ning, Zhao, Ming, Wanggou, Siyi, Luo, Weiren, Wang, Lei, Zhu, Bin, Zuo, Xiang, Xie, Wen, Zhao, Cong, Zhou, Yao, Luo, Longlong, Gao, Xiang, Jiang, Xingjun, Ren, Caiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9909993/
https://www.ncbi.nlm.nih.gov/pubmed/36778110
http://dx.doi.org/10.7150/ijbs.79095