Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs)

[Image: see text] The class I histone deacetylase (HDAC) enzymes;HDAC1,2 and 3 form the catalytic engine of at least seven structurally distinct multiprotein complexes in cells. These molecular machines play a vital role in the regulation of chromatin accessibility and gene activity via the removal...

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Detalles Bibliográficos
Autores principales: Baker, India M., Smalley, Joshua P., Sabat, Khadija A., Hodgkinson, James T., Cowley, Shaun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910044/
https://www.ncbi.nlm.nih.gov/pubmed/35948047
http://dx.doi.org/10.1021/acs.biochem.2c00288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910044/
https://www.ncbi.nlm.nih.gov/pubmed/35948047
http://dx.doi.org/10.1021/acs.biochem.2c00288

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