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Decoding the Role of MDM2 as a Potential Ubiquitin E3 Ligase and Identifying the Therapeutic Efficiency of Alkaloids against MDM2 in Combating Glioblastoma

[Image: see text] Glioblastomas (GBMs) represent the most aggressive form of brain tumor arising from the malignant transformation of astrocytes. Despite various advancements, treatment options remain limited to chemotherapy and radiotherapy followed by surgery giving an overall survival of 14–15 mo...

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Detalles Bibliográficos
Autores principales: Sharma, Sudhanshu, Kumar, Pravir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910072/
https://www.ncbi.nlm.nih.gov/pubmed/36777618
http://dx.doi.org/10.1021/acsomega.2c07904