p53 inhibits CTR1-mediated cisplatin absorption by suppressing SP1 nuclear translocation in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is a malignant bone tumor mainly affecting children and young adolescents. Cisplatin is a first-line chemotherapy drug for OS, however, drug resistance severely limits the survival of OS. Nevertheless, cellular factors in cisplatin resistance for OS remain obscure. In t...

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Detalles Bibliográficos
Autores principales: Yong, Lei, Shi, Yan, Wu, Hai-Long, Dong, Qi-Yuan, Guo, Jing, Hu, Li-Sheng, Wang, Wen-Hao, Guan, Zhi-Ping, Yu, Bin-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910081/
https://www.ncbi.nlm.nih.gov/pubmed/36776364
http://dx.doi.org/10.3389/fonc.2022.1047194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910081/
https://www.ncbi.nlm.nih.gov/pubmed/36776364
http://dx.doi.org/10.3389/fonc.2022.1047194

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