Progranulin deficiency suppresses allergic asthma and enhances efferocytosis via PPAR‐γ/MFG‐E8 regulation in macrophages

Efferocytosis can resolve airway inflammation and enhance airway tolerance in allergic asthma. While previous work has reported that progranulin (PGRN) regulated macrophage efferocytosis, but it is unclear whether PGRN‐mediated efferocytosis is associated with asthma. Here, we found that in an ovalb...

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Detalles Bibliográficos
Autores principales: Huang, Qi, Weng, Danlin, Yao, Shifei, Shen, Hailan, Gao, Song, Zhang, Yanyu, Huang, Wenjie, Wang, Yan, Wang, Hong, Xu, Wenchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910167/
https://www.ncbi.nlm.nih.gov/pubmed/36840485
http://dx.doi.org/10.1002/iid3.779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910167/
https://www.ncbi.nlm.nih.gov/pubmed/36840485
http://dx.doi.org/10.1002/iid3.779

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