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Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox”
INTRODUCTION: The incidence of obesity, a condition characterized by systemic chronic inflammation, has reached pandemic proportions and is a poor prognostic factor in many pathologic states. However, its role on immune parameters has been diverse and at times contradictory. We have previously demon...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910174/ https://www.ncbi.nlm.nih.gov/pubmed/36776393 http://dx.doi.org/10.3389/fimmu.2022.1012016 |